Nanoparticle Conjugation of Ginsenoside Rg3 Inhibits Hepatocellular Carcinoma Development and Metastasis
نویسندگان
چکیده
منابع مشابه
Antitumor effects of ginsenoside Rg3 on human hepatocellular carcinoma cells.
The antitumor effects of ginsenoside Rg3 have been reported in several kinds of human malignant tumors. The purpose of this study was to investigate whether ginsenoside Rg3 can inhibit the growth of human hepatocellular carcinoma cell lines and to discuss the possible molecular mechanism(s). We cultured the human hepatocellular carcinoma cell lines, SMMC-7721 and HepG2. The cells were treated w...
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College of Pharmacy, Inje University, 607 Obang-dong, Gimhae, Gyeongnam 621-749, Korea. *E-mail: [email protected] †Natural Products Research Institute, College of Pharmacy, Seoul National University, Seoul 151-742, Korea ‡Research Institute of Pharmaceutical Sciences and College of Pharmacy, Seoul National University, Seoul 151-742, Korea §Division of Applied Biosciences, College of Agricultu...
متن کاملGinsenoside Rg3 inhibit hepatocellular carcinoma growth via intrinsic apoptotic pathway.
AIM To investigate the anti-tumor function of ginsenoside Rg3 on hepatocellular carcinoma (HCC) in vitro and in vivo, and its mechanism. METHODS Hep1-6 and HepG2 cells were treated by Rg3 in different concentrations (0, 50, 100 and 200 μg/mL) in vitro. After incubation for 0, 6, 12, 24 and 48 h, cell viability was measured by 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide assa...
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Hepatocellular carcinoma (HCC) is the most common liver cancer, with a very poor prognosis. There is an urgent need for an effective therapy for HCC. Ginsenoside Rh2 (GRh2) has been shown to significantly inhibit growth of some types of cancer, whereas its effects on HCC have not been examined. Here, we treated human HCC cells with different doses of GRh2, and found that GRh2 dose-dependently r...
متن کاملInhibitory effect of ginsenoside Rg3 on ovarian cancer metastasis.
BACKGROUND Ginsenosides are main components extracted from ginseng, and ginsenoside Rg3 is one of the most important parts. Ginsenoside Rg3 has been found to inhibit several kinds of tumor growth and metastasis. The present study was undertaken to investigate the effect of ginsenoside Rg3 on human ovarian cancer metastasis and the possible mechanism. METHODS The experimental lung metastasis m...
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ژورنال
عنوان ژورنال: Small
سال: 2019
ISSN: 1613-6810,1613-6829
DOI: 10.1002/smll.201905233